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2rs7

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==Solution structure of the second dsRBD from RNA helicase A==
==Solution structure of the second dsRBD from RNA helicase A==
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<StructureSection load='2rs7' size='340' side='right' caption='[[2rs7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2rs7' size='340' side='right'caption='[[2rs7]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2rs7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RS7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RS7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2rs7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RS7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RS7 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rs6|2rs6]], [[1uil|1uil]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rs7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rs7 OCA], [https://pdbe.org/2rs7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rs7 RCSB], [https://www.ebi.ac.uk/pdbsum/2rs7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rs7 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dhx9, Ddx9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rs7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rs7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rs7 RCSB], [http://www.ebi.ac.uk/pdbsum/2rs7 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DHX9_MOUSE DHX9_MOUSE]] Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (By similarity).
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[https://www.uniprot.org/uniprot/DHX9_MOUSE DHX9_MOUSE] Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2rs7" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Helicase|Helicase]]
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*[[Helicase 3D structures|Helicase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: RNA helicase]]
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[[Category: Inoue M]]
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[[Category: Inoue, M]]
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[[Category: Kigawa T]]
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[[Category: Kigawa, T]]
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[[Category: Muto Y]]
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[[Category: Muto, Y]]
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[[Category: Nagata T]]
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[[Category: Nagata, T]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M]]
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[[Category: Terada T]]
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[[Category: Terada, T]]
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[[Category: Tsuda K]]
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[[Category: Tsuda, K]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Double-stranded rna binding domain]]
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[[Category: Dsrbd]]
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[[Category: Dsrm]]
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[[Category: Hydrolase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Structural genomic]]
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[[Category: Rsgi]]
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Current revision

Solution structure of the second dsRBD from RNA helicase A

PDB ID 2rs7

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