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4a67

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==Mutations in the neighbourhood of CotA-laccase trinuclear site: D116E mutant==
==Mutations in the neighbourhood of CotA-laccase trinuclear site: D116E mutant==
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<StructureSection load='4a67' size='340' side='right' caption='[[4a67]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4a67' size='340' side='right'caption='[[4a67]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4a67]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A67 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4a67]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A67 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A67 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=PER:PEROXIDE+ION'>PER</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=PER:PEROXIDE+ION'>PER</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1uvw|1uvw]], [[1of0|1of0]], [[1w6w|1w6w]], [[2x88|2x88]], [[4a68|4a68]], [[1w8e|1w8e]], [[4a66|4a66]], [[1gsk|1gsk]], [[1w6l|1w6l]], [[2x87|2x87]], [[2bhf|2bhf]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a67 OCA], [https://pdbe.org/4a67 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a67 RCSB], [https://www.ebi.ac.uk/pdbsum/4a67 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a67 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Laccase Laccase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a67 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a67 RCSB], [http://www.ebi.ac.uk/pdbsum/4a67 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/COTA_BACSU COTA_BACSU]] Involved in brown pigmentation during sporogenesis.
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[https://www.uniprot.org/uniprot/COTA_BACSU COTA_BACSU] Involved in brown pigmentation during sporogenesis.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4a67" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[CotA laccase|CotA laccase]]
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*[[Laccase 3D structures|Laccase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Laccase]]
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[[Category: Large Structures]]
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[[Category: Bento, I]]
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[[Category: Bento I]]
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[[Category: Lindley, P F]]
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[[Category: Lindley PF]]
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[[Category: Silva, C S]]
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[[Category: Silva CS]]
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[[Category: Dioxygen reduction]]
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[[Category: Multi-copper oxidase]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase activity]]
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[[Category: Trinuclear cluster]]
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Current revision

Mutations in the neighbourhood of CotA-laccase trinuclear site: D116E mutant

PDB ID 4a67

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