Llama Antibody Inhibits Botulinum Neruotoxin
From Proteopedia
| (One intermediate revision not shown.) | |||
| Line 12: | Line 12: | ||
==Botulinum Toxin== | ==Botulinum Toxin== | ||
[[Image:Figure1.png|left|300px]] | [[Image:Figure1.png|left|300px]] | ||
| - | Botulinum Toxin is very deadly in a sense that it prevents muscle contraction. Botulinum toxin prevents the release of [http://en.wikipedia.org/wiki/Acetylcholine#Function Acetylcholine]into the synaptic cleft to relay the signaling to another neuron. Acetylcholine has functions both in the peripheral nervous system (PNS) and in the central nervous system (CNS) as a neuromodulator.In the peripheral nervous system, acetylcholine activates muscles, and is a major neurotransmitter in the autonomic nervous system.In the central nervous system, acetylcholine and the associated neurons form a neurotransmitter system, the cholinergic system, which tends to cause anti-excitatory actions. [http://www.youtube.com/watch?v=6n3rrjbweO8 Mechanism of Botulinum Toxin] | + | Botulinum Toxin is very deadly in a sense that it prevents muscle contraction. [[Botulinum neurotoxin|Botulinum toxin]] prevents the release of [http://en.wikipedia.org/wiki/Acetylcholine#Function Acetylcholine]into the synaptic cleft to relay the signaling to another neuron. Acetylcholine has functions both in the peripheral nervous system (PNS) and in the central nervous system (CNS) as a neuromodulator.In the peripheral nervous system, acetylcholine activates muscles, and is a major neurotransmitter in the autonomic nervous system.In the central nervous system, acetylcholine and the associated neurons form a neurotransmitter system, the cholinergic system, which tends to cause anti-excitatory actions. [http://www.youtube.com/watch?v=6n3rrjbweO8 Mechanism of Botulinum Toxin] |
Current revision
Clostridium Botulinum
C. botulinum bacteria, which are commonly found in soil, can form spores that allow them to survive in a dormant state until they're exposed to conditions that support their growth. Infant botulism, the most common type of botulism, occurs when infants consume these spores, which then grow in their intestines and release toxin. In adults, most outbreaks are caused by contaminated home-canned foods. You can also get botulism through contaminated wounds.
If diagnosed early, botulism can be treated with an antitoxin, which blocks the action of the toxin in the blood. But recovery still takes many months. The antitoxin can also cause serious side effects, has only a very short window of application and is expensive to produce in large enough quantities to combat a bioterrorism attack.
Botulinum Toxin
Botulinum Toxin is very deadly in a sense that it prevents muscle contraction. Botulinum toxin prevents the release of Acetylcholineinto the synaptic cleft to relay the signaling to another neuron. Acetylcholine has functions both in the peripheral nervous system (PNS) and in the central nervous system (CNS) as a neuromodulator.In the peripheral nervous system, acetylcholine activates muscles, and is a major neurotransmitter in the autonomic nervous system.In the central nervous system, acetylcholine and the associated neurons form a neurotransmitter system, the cholinergic system, which tends to cause anti-excitatory actions. Mechanism of Botulinum Toxin
Llama Antibody Inhibits Botulinum Neruotoxin
| |||||||||||
