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3dih

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==Crystal structure of ammodytin L==
==Crystal structure of ammodytin L==
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<StructureSection load='3dih' size='340' side='right' caption='[[3dih]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='3dih' size='340' side='right'caption='[[3dih]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3dih]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vipera_ammodytes_ammodytes Vipera ammodytes ammodytes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DIH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3dih]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vipera_ammodytes_ammodytes Vipera ammodytes ammodytes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DIH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3DIH FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dih RCSB], [http://www.ebi.ac.uk/pdbsum/3dih PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3dih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dih OCA], [http://pdbe.org/3dih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dih RCSB], [http://www.ebi.ac.uk/pdbsum/3dih PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dih ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PA2L_VIPAA PA2L_VIPAA]] Snake venom phospholipase A2 homolog that is very active in inducing myonecrosis in vivo and shows a potent calcium-independent membrane-damaging activity in vitro, most probably by binding and incorporating in the membrane. Also acts as a presynaptic neurotoxin.<ref>PMID:1765075</ref> <ref>PMID:7662700</ref> <ref>PMID:8835336</ref> <ref>PMID:8973554</ref> <ref>PMID:9514950</ref> <ref>PMID:10653156</ref> <ref>PMID:11005629</ref> <ref>PMID:17927217</ref>
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[[http://www.uniprot.org/uniprot/PA2HL_VIPAA PA2HL_VIPAA]] Snake venom phospholipase A2 homolog that is very active in inducing myonecrosis in vivo and shows a potent calcium-independent membrane-damaging activity in vitro, most probably by binding and incorporating in the membrane. Also acts as a presynaptic neurotoxin.<ref>PMID:10653156</ref> <ref>PMID:11005629</ref> <ref>PMID:1765075</ref> <ref>PMID:17927217</ref> <ref>PMID:7662700</ref> <ref>PMID:8835336</ref> <ref>PMID:8973554</ref> <ref>PMID:9514950</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/di/3dih_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/di/3dih_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dih ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phospholipase A2|Phospholipase A2]]
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
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*[[Phospholipase A2 homolog|Phospholipase A2 homolog]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Vipera ammodytes ammodytes]]
[[Category: Vipera ammodytes ammodytes]]
[[Category: Guncar, G]]
[[Category: Guncar, G]]

Current revision

Crystal structure of ammodytin L

PDB ID 3dih

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