This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2rmm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (19:14, 29 May 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Solution structure of GB1 A34F mutant==
==Solution structure of GB1 A34F mutant==
-
<StructureSection load='2rmm' size='340' side='right' caption='[[2rmm]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='2rmm' size='340' side='right'caption='[[2rmm]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2rmm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_sp._'group_g' Streptococcus sp. 'group g']. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RMM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RMM FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2rmm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_sp._'group_G' Streptococcus sp. 'group G']. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RMM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RMM FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">spg ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1320 Streptococcus sp. 'group G'])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rmm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rmm RCSB], [http://www.ebi.ac.uk/pdbsum/2rmm PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rmm OCA], [https://pdbe.org/2rmm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rmm RCSB], [https://www.ebi.ac.uk/pdbsum/2rmm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rmm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/SPG1_STRSG SPG1_STRSG]] Binds to the constant Fc region of IgG with high affinity.
+
[https://www.uniprot.org/uniprot/SPG1_STRSG SPG1_STRSG] Binds to the constant Fc region of IgG with high affinity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rm/2rmm_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rm/2rmm_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rmm ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
Line 23: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Streptococcus sp. 'group g']]
+
[[Category: Large Structures]]
-
[[Category: Byeon, I]]
+
[[Category: Streptococcus sp. 'group G']]
-
[[Category: Gronenborn, A M]]
+
[[Category: Byeon I]]
-
[[Category: Jee, J]]
+
[[Category: Gronenborn AM]]
-
[[Category: Louis, J M]]
+
[[Category: Jee J]]
-
[[Category: Cell wall]]
+
[[Category: Louis JM]]
-
[[Category: Gb1 mutant]]
+
-
[[Category: Igg-binding protein]]
+
-
[[Category: Immune system]]
+
-
[[Category: Peptidoglycan-anchor]]
+
-
[[Category: Secreted]]
+

Current revision

Solution structure of GB1 A34F mutant

PDB ID 2rmm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools