We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

2cz0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (22:20, 26 March 2025) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2cz0.gif|left|200px]]
 
-
{{Structure
+
==photo-activation state of Fe-type NHase in aerobic condition==
-
|PDB= 2cz0 |SIZE=350|CAPTION= <scene name='initialview01'>2cz0</scene>, resolution 1.50&Aring;
+
<StructureSection load='2cz0' size='340' side='right'caption='[[2cz0]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene> and <scene name='pdbligand=BUA:BUTANOIC ACID'>BUA</scene>
+
<table><tr><td colspan='2'>[[2cz0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ0 FirstGlance]. <br>
-
|ACTIVITY= [http://en.wikipedia.org/wiki/Nitrile_hydratase Nitrile hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.84 4.2.1.84]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BUA:BUTANOIC+ACID'>BUA</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz0 OCA], [https://pdbe.org/2cz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz0 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz0 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz0 TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/NHAA_RHOER NHAA_RHOER] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2cz0_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cz0 ConSurf].
 +
<div style="clear:both"></div>
-
'''photo-activation state of Fe-type NHase in aerobic condition'''
+
==See Also==
-
 
+
*[[Nitrile hydratase|Nitrile hydratase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2CZ0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ0 OCA].
+
[[Category: Large Structures]]
-
[[Category: Nitrile hydratase]]
+
-
[[Category: Protein complex]]
+
[[Category: Rhodococcus erythropolis]]
[[Category: Rhodococcus erythropolis]]
-
[[Category: Endo, I.]]
+
[[Category: Endo I]]
-
[[Category: Hashimoto, K.]]
+
[[Category: Hashimoto K]]
-
[[Category: Kamiya, N.]]
+
[[Category: Kamiya N]]
-
[[Category: Kawano, Y.]]
+
[[Category: Kawano Y]]
-
[[Category: Nakayama, H.]]
+
[[Category: Nakayama H]]
-
[[Category: Odaka, M.]]
+
[[Category: Odaka M]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Takio K]]
-
[[Category: Takio, K.]]
+
-
[[Category: BUA]]
+
-
[[Category: FE]]
+
-
[[Category: cysteine-sulfenic acid]]
+
-
[[Category: cysteine-sulfinic acid]]
+
-
[[Category: hydration]]
+
-
[[Category: national project on protein structural and functional analyse]]
+
-
[[Category: nitrile]]
+
-
[[Category: non-hem iron]]
+
-
[[Category: nppsfa]]
+
-
[[Category: over-oxidization]]
+
-
[[Category: photo-reactive]]
+
-
[[Category: post-translational modification]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:21:21 2008''
+

Current revision

photo-activation state of Fe-type NHase in aerobic condition

PDB ID 2cz0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2cz0"
Personal tools