4kzm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:54, 20 March 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal Structure of TR3 LBD S553A Mutant==
==Crystal Structure of TR3 LBD S553A Mutant==
-
<StructureSection load='4kzm' size='340' side='right' caption='[[4kzm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+
<StructureSection load='4kzm' size='340' side='right'caption='[[4kzm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4kzm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KZM FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4kzm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KZM FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kzi|4kzi]], [[4kzj|4kzj]], [[4jgv|4jgv]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GFRP1, HMR, NAK1, NR4A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kzm OCA], [https://pdbe.org/4kzm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kzm RCSB], [https://www.ebi.ac.uk/pdbsum/4kzm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kzm ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kzm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kzm RCSB], [http://www.ebi.ac.uk/pdbsum/4kzm PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
+
[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Cai, Q]]
+
[[Category: Large Structures]]
-
[[Category: Chen, H]]
+
[[Category: Cai Q]]
-
[[Category: Li, A]]
+
[[Category: Chen H]]
-
[[Category: Li, F]]
+
[[Category: Li A]]
-
[[Category: Lin, T]]
+
[[Category: Li F]]
-
[[Category: Tian, X]]
+
[[Category: Lin T]]
-
[[Category: Wang, W]]
+
[[Category: Tian X]]
-
[[Category: Wang, Y]]
+
[[Category: Wang W]]
-
[[Category: Wu, Q]]
+
[[Category: Wang Y]]
-
[[Category: Xing, Y]]
+
[[Category: Wu Q]]
-
[[Category: Zhang, Q]]
+
[[Category: Xing Y]]
-
[[Category: Orphan nuclear receptor]]
+
[[Category: Zhang Q]]
-
[[Category: Transcription]]
+

Current revision

Crystal Structure of TR3 LBD S553A Mutant

PDB ID 4kzm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4kzm"
Personal tools