2d63

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[[Image:2d63.gif|left|200px]]
 
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{{Structure
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==Aspartate Aminotransferase Mutant MA With Isovaleric Acid==
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|PDB= 2d63 |SIZE=350|CAPTION= <scene name='initialview01'>2d63</scene>, resolution 2.05&Aring;
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<StructureSection load='2d63' size='340' side='right'caption='[[2d63]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene> and <scene name='pdbligand=IVA:ISOVALERIC ACID'>IVA</scene>
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<table><tr><td colspan='2'>[[2d63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D63 FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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|GENE= aspC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IVA:ISOVALERIC+ACID'>IVA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d63 OCA], [https://pdbe.org/2d63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d63 RCSB], [https://www.ebi.ac.uk/pdbsum/2d63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d63 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AAT_ECOLI AAT_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d6/2d63_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d63 ConSurf].
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<div style="clear:both"></div>
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'''Aspartate Aminotransferase Mutant MA With Isovaleric Acid'''
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==See Also==
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*[[Aspartate aminotransferase 3D structures|Aspartate aminotransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2D63 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D63 OCA].
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[[Category: Aspartate transaminase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu S]]
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[[Category: Masui, R.]]
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[[Category: Masui R]]
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[[Category: Nakagawa, N.]]
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[[Category: Nakagawa N]]
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[[Category: Tada, H.]]
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[[Category: Tada H]]
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[[Category: Tanaka, Y.]]
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[[Category: Tanaka Y]]
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[[Category: Yano, T.]]
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[[Category: Yano T]]
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[[Category: IVA]]
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[[Category: PLP]]
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[[Category: aspartate aminotransferase]]
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[[Category: directed evolution]]
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[[Category: protein design]]
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[[Category: protein enginnering]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:23:46 2008''
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Current revision

Aspartate Aminotransferase Mutant MA With Isovaleric Acid

PDB ID 2d63

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OCA

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