This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4tvw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (00:48, 28 December 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Resorufin ligase with bound resorufin-AMP analog==
==Resorufin ligase with bound resorufin-AMP analog==
-
<StructureSection load='4tvw' size='340' side='right' caption='[[4tvw]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
+
<StructureSection load='4tvw' size='340' side='right'caption='[[4tvw]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4tvw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TVW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TVW FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4tvw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TVW FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=37P:5-O-{[5-(7-HYDROXY-3-OXO-3H-PHENOXAZIN-2-YL)PENTANOYL]SULFAMOYL}ADENOSINE'>37P</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.505&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3a7r|3a7r]], [[4tvy|4tvy]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=37P:5-O-{[5-(7-HYDROXY-3-OXO-3H-PHENOXAZIN-2-YL)PENTANOYL]SULFAMOYL}ADENOSINE'>37P</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.63 2.7.7.63] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tvw OCA], [https://pdbe.org/4tvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tvw RCSB], [https://www.ebi.ac.uk/pdbsum/4tvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tvw ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tvw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tvw RCSB], [http://www.ebi.ac.uk/pdbsum/4tvw PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/LPLA_ECOLI LPLA_ECOLI]] Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to catalyze very poorly the transfer of lipoyl and octanoyl moiety from their acyl carrier protein.<ref>PMID:7639702</ref>
+
[https://www.uniprot.org/uniprot/LPLA_ECOLI LPLA_ECOLI] Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to catalyze very poorly the transfer of lipoyl and octanoyl moiety from their acyl carrier protein.<ref>PMID:7639702</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4tvw" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Transferase]]
+
[[Category: Escherichia coli]]
-
[[Category: Drennan, C L]]
+
[[Category: Large Structures]]
-
[[Category: Goldman, P J]]
+
[[Category: Drennan CL]]
-
[[Category: Computational enzyme design]]
+
[[Category: Goldman PJ]]
-
[[Category: E. coli lpla]]
+

Current revision

Resorufin ligase with bound resorufin-AMP analog

PDB ID 4tvw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4tvw"
Personal tools