2ddj

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[[Image:2ddj.jpg|left|200px]]
 
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{{Structure
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==NMR structure of the second Kunitz domain of human WFIKKN1==
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|PDB= 2ddj |SIZE=350|CAPTION= <scene name='initialview01'>2ddj</scene>
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<StructureSection load='2ddj' size='340' side='right'caption='[[2ddj]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2ddj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDJ FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
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|GENE= WFIKKN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ddj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ddj OCA], [https://pdbe.org/2ddj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ddj RCSB], [https://www.ebi.ac.uk/pdbsum/2ddj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ddj ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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'''NMR structure of the second Kunitz domain of human WFIKKN1'''
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[https://www.uniprot.org/uniprot/WFKN1_HUMAN WFKN1_HUMAN] Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2DDJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDJ OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dd/2ddj_consurf.spt"</scriptWhenChecked>
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==Reference==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein., Liepinsh E, Nagy A, Trexler M, Patthy L, Otting G, J Biomol NMR. 2006 May;35(1):73-8. Epub 2006 Jun 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16791741 16791741]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ddj ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Liepinsh, E.]]
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[[Category: Liepinsh E]]
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[[Category: Otting, G.]]
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[[Category: Otting G]]
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[[Category: kunitz domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:26:02 2008''
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Current revision

NMR structure of the second Kunitz domain of human WFIKKN1

PDB ID 2ddj

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OCA

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