2dgx

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[[Image:2dgx.gif|left|200px]]
 
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{{Structure
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==Solution structure of the RNA recognition motif in KIAA0430 protein==
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|PDB= 2dgx |SIZE=350|CAPTION= <scene name='initialview01'>2dgx</scene>
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<StructureSection load='2dgx' size='340' side='right'caption='[[2dgx]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2dgx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DGX FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= KIAA0430 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dgx OCA], [https://pdbe.org/2dgx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dgx RCSB], [https://www.ebi.ac.uk/pdbsum/2dgx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dgx ProSAT], [https://www.topsan.org/Proteins/RSGI/2dgx TOPSAN]</span></td></tr>
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}}
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</table>
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== Function ==
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'''Solution structure of the RNA recognition motif in KIAA0430 protein'''
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[https://www.uniprot.org/uniprot/MARF1_HUMAN MARF1_HUMAN] Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity).
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__TOC__
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</StructureSection>
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==About this Structure==
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2DGX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DGX OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Abe, C.]]
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[[Category: Abe C]]
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[[Category: Inoue, M.]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa T]]
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[[Category: Muto, Y.]]
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[[Category: Muto Y]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M.]]
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[[Category: Terada T]]
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[[Category: Terada, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: national project on protein structural and functional analyse]]
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[[Category: nppsfa]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rrm domain]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:27:05 2008''
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Current revision

Solution structure of the RNA recognition motif in KIAA0430 protein

PDB ID 2dgx

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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