We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

3l9x

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:33, 6 September 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==KefC C-terminal domain in complex with KefF and ESG==
==KefC C-terminal domain in complex with KefF and ESG==
-
<StructureSection load='3l9x' size='340' side='right' caption='[[3l9x]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+
<StructureSection load='3l9x' size='340' side='right'caption='[[3l9x]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3l9x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L9X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L9X FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3l9x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L9X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L9X FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ESG:L-GAMMA-GLUTAMYL-S-[(3S)-1-ETHYL-2,5-DIOXOPYRROLIDIN-3-YL]-L-CYSTEINYLGLYCINE'>ESG</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=L9X:L-GAMMA-GLUTAMYL-S-[(3R)-1-ETHYL-2,5-DIOXOPYRROLIDIN-3-YL]-L-CYSTEINYLGLYCINE'>L9X</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3l9w|3l9w]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ESG:L-GAMMA-GLUTAMYL-S-[(3S)-1-ETHYL-2,5-DIOXOPYRROLIDIN-3-YL]-L-CYSTEINYLGLYCINE'>ESG</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=L9X:L-GAMMA-GLUTAMYL-S-[(3R)-1-ETHYL-2,5-DIOXOPYRROLIDIN-3-YL]-L-CYSTEINYLGLYCINE'>L9X</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0047, JW0046, kefC, trkC, b0046, JW0045, kefF, yabF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l9x OCA], [https://pdbe.org/3l9x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l9x RCSB], [https://www.ebi.ac.uk/pdbsum/3l9x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l9x ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l9x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l9x RCSB], [http://www.ebi.ac.uk/pdbsum/3l9x PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/KEFC_ECOLI KEFC_ECOLI]] Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport.
+
[https://www.uniprot.org/uniprot/KEFC_ECOLI KEFC_ECOLI] Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport.[https://www.uniprot.org/uniprot/KEFF_ECOLI KEFF_ECOLI] Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC. Can use a wide range of substrates, including electrophilic quinones, and its function could be to reduce the redox toxicity of electrophilic quinones in parallel with acting as triggers for the KefC efflux system.[HAMAP-Rule:MF_01414]<ref>PMID:11053405</ref> <ref>PMID:19523906</ref> <ref>PMID:21742892</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 3l9x" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Escherichia coli]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Roosild, T P]]
+
[[Category: Large Structures]]
-
[[Category: Glutathione]]
+
[[Category: Roosild TP]]
-
[[Category: Potassium channel regulation]]
+
-
[[Category: Potassium efflux]]
+
-
[[Category: Transport protein]]
+

Current revision

KefC C-terminal domain in complex with KefF and ESG

PDB ID 3l9x

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3l9x"
Personal tools