2dmr

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[[Image:2dmr.gif|left|200px]]
 
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{{Structure
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==DITHIONITE REDUCED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS==
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|PDB= 2dmr |SIZE=350|CAPTION= <scene name='initialview01'>2dmr</scene>, resolution 2.8&Aring;
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<StructureSection load='2dmr' size='340' side='right'caption='[[2dmr]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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|SITE= <scene name='pdbsite=MO:SER+Site'>MO</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=PGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>PGD</scene>, <scene name='pdbligand=4MO:MOLYBDENUM(IV)+ION'>4MO</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene> and <scene name='pdbligand=SO2:SULFUR DIOXIDE'>SO2</scene>
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<table><tr><td colspan='2'>[[2dmr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DMR FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MO:MOLYBDENUM(IV)+ION'>4MO</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene>, <scene name='pdbligand=PGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>PGD</scene>, <scene name='pdbligand=SO2:SULFUR+DIOXIDE'>SO2</scene></td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dmr OCA], [https://pdbe.org/2dmr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dmr RCSB], [https://www.ebi.ac.uk/pdbsum/2dmr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dmr ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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'''DITHIONITE REDUCED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS'''
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[https://www.uniprot.org/uniprot/DSTOR_RHOCA DSTOR_RHOCA] Catalyzes the reduction of dimethyl sulfoxide (DMSO) and trimethylamine N-oxide (TMAO) to dimethyl sulfide (DMS) and trimethylamine, respectively. The terminal DMSO reductase can also use various sulfoxides and N-oxide compounds as terminal electron acceptor in addition to DMSO and TMAO.<ref>PMID:2001248</ref> <ref>PMID:8856102</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2DMR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMR OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dm/2dmr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dmr ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rhodobacter capsulatus]]
[[Category: Rhodobacter capsulatus]]
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[[Category: Single protein]]
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[[Category: Bailey S]]
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[[Category: Bailey, S.]]
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[[Category: Mcalpine AS]]
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[[Category: Mcalpine, A S.]]
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[[Category: 4MO]]
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[[Category: O]]
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[[Category: PGD]]
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[[Category: SO2]]
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[[Category: dithionite]]
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[[Category: dmso]]
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[[Category: molybdopterin]]
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[[Category: monoxo]]
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[[Category: reductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:29:00 2008''
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Current revision

DITHIONITE REDUCED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS

PDB ID 2dmr

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