This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2wsd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:15, 20 December 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
==PROXIMAL MUTATIONS AT THE TYPE 1 CU SITE OF COTA-LACCASE: I494A MUTANT==
+
 
-
<StructureSection load='2wsd' size='340' side='right' caption='[[2wsd]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+
==Proximal mutations at the type 1 Cu site of CotA-laccase: I494A mutant==
 +
<StructureSection load='2wsd' size='340' side='right'caption='[[2wsd]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2wsd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WSD FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2wsd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WSD FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w6l|1w6l]], [[1gsk|1gsk]], [[1uvw|1uvw]], [[2bhf|2bhf]], [[1of0|1of0]], [[1w6w|1w6w]], [[1w8e|1w8e]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsd OCA], [https://pdbe.org/2wsd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wsd RCSB], [https://www.ebi.ac.uk/pdbsum/2wsd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wsd ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Laccase Laccase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wsd RCSB], [http://www.ebi.ac.uk/pdbsum/2wsd PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/COTA_BACSU COTA_BACSU]] Involved in brown pigmentation during sporogenesis.
+
[https://www.uniprot.org/uniprot/COTA_BACSU COTA_BACSU] Involved in brown pigmentation during sporogenesis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ws/2wsd_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ws/2wsd_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wsd ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 29: Line 28:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2wsd" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[CotA laccase|CotA laccase]]
+
*[[Laccase 3D structures|Laccase 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 37: Line 37:
</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
-
[[Category: Laccase]]
+
[[Category: Large Structures]]
-
[[Category: Bento, I]]
+
[[Category: Bento I]]
-
[[Category: Chen, Z]]
+
[[Category: Chen Z]]
-
[[Category: Durao, P]]
+
[[Category: Durao P]]
-
[[Category: Hildebrandt, P]]
+
[[Category: Hildebrandt P]]
-
[[Category: Lindley, P F]]
+
[[Category: Lindley PF]]
-
[[Category: Martins, L O]]
+
[[Category: Martins LO]]
-
[[Category: Pereira, M M]]
+
[[Category: Pereira MM]]
-
[[Category: Silva, C S]]
+
[[Category: Silva CS]]
-
[[Category: Soares, C M]]
+
[[Category: Soares CM]]
-
[[Category: Todorovic, S]]
+
[[Category: Todorovic S]]
-
[[Category: Cota- laccase]]
+
-
[[Category: Multi-copper oxidase]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Sporulation]]
+
-
[[Category: T1 copper centre]]
+

Current revision

Proximal mutations at the type 1 Cu site of CotA-laccase: I494A mutant

PDB ID 2wsd

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2wsd"
Personal tools