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1ufi

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==Crystal structure of the dimerization domain of human CENP-B==
==Crystal structure of the dimerization domain of human CENP-B==
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<StructureSection load='1ufi' size='340' side='right' caption='[[1ufi]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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<StructureSection load='1ufi' size='340' side='right'caption='[[1ufi]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ufi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UFI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ufi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UFI FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CENPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ufi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ufi RCSB], [http://www.ebi.ac.uk/pdbsum/1ufi PDBsum], [http://www.topsan.org/Proteins/RSGI/1ufi TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ufi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufi OCA], [https://pdbe.org/1ufi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ufi RCSB], [https://www.ebi.ac.uk/pdbsum/1ufi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ufi ProSAT], [https://www.topsan.org/Proteins/RSGI/1ufi TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CENPB_HUMAN CENPB_HUMAN]] Interacts with centromeric heterochromatin in chromosomes and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
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[https://www.uniprot.org/uniprot/CENPB_HUMAN CENPB_HUMAN] Interacts with centromeric heterochromatin in chromosomes and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1ufi" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Centromere protein|Centromere protein]]
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*[[Centromere protein 3D structure|Centromere protein 3D structure]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kurumizaka, H]]
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[[Category: Large Structures]]
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[[Category: Park, S Y]]
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[[Category: Kurumizaka H]]
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[[Category: Structural genomic]]
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[[Category: Park S-Y]]
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[[Category: Tanaka, Y]]
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[[Category: Tanaka Y]]
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[[Category: Tawaramoto, M S]]
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[[Category: Tawaramoto MS]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Dimerization domain]]
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[[Category: Dna binding protein]]
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[[Category: Rsgi]]
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[[Category: Salt bridge]]
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Current revision

Crystal structure of the dimerization domain of human CENP-B

PDB ID 1ufi

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