1cjg

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==NMR STRUCTURE OF LAC REPRESSOR HP62-DNA COMPLEX==
==NMR STRUCTURE OF LAC REPRESSOR HP62-DNA COMPLEX==
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<StructureSection load='1cjg' size='340' side='right' caption='[[1cjg]], [[NMR_Ensembles_of_Models | 11 NMR models]]' scene=''>
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<StructureSection load='1cjg' size='340' side='right'caption='[[1cjg]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1cjg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CJG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1cjg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CJG FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LAC I, THE PART ENCODING THE 62 N-TERMINAL AMINOACIDS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cjg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cjg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cjg RCSB], [http://www.ebi.ac.uk/pdbsum/1cjg PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cjg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cjg OCA], [https://pdbe.org/1cjg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cjg RCSB], [https://www.ebi.ac.uk/pdbsum/1cjg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cjg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI]] Repressor of the lactose operon. Binds allolactose as an inducer.
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[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI] Repressor of the lactose operon. Binds allolactose as an inducer.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/1cjg_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/1cjg_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cjg ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1cjg" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Lac repressor 3D structures|Lac repressor 3D structures]]
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*[[Lac repressor|Lac repressor]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Boelens, R]]
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[[Category: Large Structures]]
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[[Category: Bonvin, A M.J J]]
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[[Category: Boelens R]]
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[[Category: Kaptein, R]]
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[[Category: Bonvin AMJJ]]
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[[Category: Melacini, G]]
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[[Category: Kaptein R]]
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[[Category: Radha, P K]]
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[[Category: Melacini G]]
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[[Category: Spronk, C A.E M]]
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[[Category: Radha PK]]
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[[Category: Headpiece]]
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[[Category: Spronk CAEM]]
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[[Category: Lac operator]]
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[[Category: Lac operon]]
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[[Category: Lac repressor]]
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[[Category: Transcription regulation]]
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[[Category: Transcription-dna complex]]
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Current revision

NMR STRUCTURE OF LAC REPRESSOR HP62-DNA COMPLEX

PDB ID 1cjg

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