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4r7u

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==Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin==
==Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin==
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<StructureSection load='4r7u' size='340' side='right' caption='[[4r7u]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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<StructureSection load='4r7u' size='340' side='right'caption='[[4r7u]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4r7u]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R7U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R7U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4r7u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R7U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FFQ:[(1R)-1-HYDROXYPROPYL]PHOSPHONIC+ACID'>FFQ</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FFQ:[(1R)-1-HYDROXYPROPYL]PHOSPHONIC+ACID'>FFQ</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r7u OCA], [https://pdbe.org/4r7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r7u RCSB], [https://www.ebi.ac.uk/pdbsum/4r7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r7u ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r7u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r7u RCSB], [http://www.ebi.ac.uk/pdbsum/4r7u PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MURA_VIBCH MURA_VIBCH]] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity).
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[https://www.uniprot.org/uniprot/MURA_VIBCH MURA_VIBCH] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity).
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==See Also==
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*[[Enoylpyruvate transferase 3D structures|Enoylpyruvate transferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
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[[Category: Large Structures]]
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[[Category: Anderson, W]]
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[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
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[[Category: Structural genomic]]
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[[Category: Anderson W]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak A]]
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[[Category: Maltseva, N]]
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[[Category: Maltseva N]]
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[[Category: Nocek, B]]
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[[Category: Nocek B]]
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[[Category: Amino sugar and nucleotide sugar metabolism]]
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[[Category: Csgid]]
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[[Category: Fosfomycin]]
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[[Category: Mura]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Peptidoglycan]]
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[[Category: Peptidoglycan biosynthesis]]
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[[Category: Transferase-antibiotic complex]]
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[[Category: Udp-n-acetylglucosamine 1-carboxyvinyltransferase]]
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Current revision

Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin

PDB ID 4r7u

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