4fo4

<StructureSection load='4fo4' size='340' side='right' caption='[[4fo4]], [[Resolution|resolution]] 2.03&Aring;' scene=''>

<table><tr><td colspan='2'>[[4fo4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o1_biovar_el_tor Vibrio cholerae o1 biovar el tor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FO4 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MOA:MYCOPHENOLIC+ACID'>MOA</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fez|4fez]], [[4ff0|4ff0]]</td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VC0767, VC_0767 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=686 Vibrio cholerae O1 biovar El Tor])</td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fo4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fo4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fo4 RCSB], [http://www.ebi.ac.uk/pdbsum/4fo4 PDBsum]</span></td></tr>

[[http://www.uniprot.org/uniprot/Q9KTW3_VIBCH Q9KTW3_VIBCH]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]

*[[Inosine monophosphate dehydrogenase|Inosine monophosphate dehydrogenase]]

[[Category: IMP dehydrogenase]]

[[Category: Vibrio cholerae o1 biovar el tor]]

[[Category: Anderson, W F]]

[[Category: Structural genomic]]

[[Category: Gu, M]]

[[Category: Joachimiak, A]]

[[Category: Makowska-Grzyska, M]]

[[Category: Maltseva, N]]

[[Category: Osipiuk, J]]

[[Category: Oxidoreductase]]