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3knu

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==Crystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum==
==Crystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum==
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<StructureSection load='3knu' size='340' side='right' caption='[[3knu]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='3knu' size='340' side='right'caption='[[3knu]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3knu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anaplasma_phagocytophilum Anaplasma phagocytophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KNU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3knu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaplasma_phagocytophilum_str._HZ Anaplasma phagocytophilum str. HZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KNU FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e5y|3e5y]], [[3ief|3ief]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmD, APH_1267 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=948 Anaplasma phagocytophilum])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3knu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3knu OCA], [https://pdbe.org/3knu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3knu RCSB], [https://www.ebi.ac.uk/pdbsum/3knu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3knu ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine-N(1)-)-methyltransferase tRNA (guanine-N(1)-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.31 2.1.1.31] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3knu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3knu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3knu RCSB], [http://www.ebi.ac.uk/pdbsum/3knu PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TRMD_ANAPZ TRMD_ANAPZ]] Specifically methylates guanosine-37 in various tRNAs (By similarity).
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[https://www.uniprot.org/uniprot/TRMD_ANAPZ TRMD_ANAPZ] Specifically methylates guanosine-37 in various tRNAs (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kn/3knu_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kn/3knu_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3knu ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[TRNA methyltransferase|TRNA methyltransferase]]
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*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anaplasma phagocytophilum]]
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[[Category: Anaplasma phagocytophilum str. HZ]]
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[[Category: Structural genomic]]
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[[Category: Large Structures]]
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[[Category: Methyltransferase]]
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[[Category: Niaid]]
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[[Category: Protein knot]]
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[[Category: Rna-binding protein]]
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[[Category: S-adenosyl-l-methionine]]
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[[Category: Ssgcid]]
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[[Category: Transferase]]
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[[Category: Trefoil knot]]
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[[Category: Trna methyl transferase]]
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[[Category: Trna processing]]
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Current revision

Crystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum

PDB ID 3knu

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