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2ei0

From Proteopedia

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[[Image:2ei0.jpg|left|200px]]
 
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{{Structure
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==Anaerobic Crystal Structure Analysis of 1,2-dihydroxynaphthalene dioxygenase from Pseudomonas sp. strain C18 complexed with 3,4-dihydroxybiphenyl==
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|PDB= 2ei0 |SIZE=350|CAPTION= <scene name='initialview01'>2ei0</scene>, resolution 1.60&Aring;
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<StructureSection load='2ei0' size='340' side='right'caption='[[2ei0]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Fe2+Binding+Site+For+Residue+A+399'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+A+398'>AC2</scene>, <scene name='pdbsite=AC3:Bp7+Binding+Site+For+Residue+A+400'>AC3</scene>, <scene name='pdbsite=AC4:Bp7+Binding+Site+For+Residue+A+401'>AC4</scene>, <scene name='pdbsite=AC5:Bp7+Binding+Site+For+Residue+A+402'>AC5</scene> and <scene name='pdbsite=AC6:Gol+Binding+Site+For+Residue+A+901'>AC6</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=BP7:'>BP7</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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<table><tr><td colspan='2'>[[2ei0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._C18 Pseudomonas sp. C18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EI0 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= doxg ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=306 Pseudomonas sp.])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BP7:1,1-BIPHENYL-3,4-DIOL'>BP7</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ei0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei0 OCA], [https://pdbe.org/2ei0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ei0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ei0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ei0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NAHC_PSEU8 NAHC_PSEU8] Involved in the naphthalene catabolic pathway. Catalyzes the meta-cleavage of 1,2-dihydroxynaphthalene (1,2-DHN) to yield 2-hydroxychromene-2-carboxylic acid (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2ei0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ei0 ConSurf].
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<div style="clear:both"></div>
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'''Anaerobic Crystal Structure Analysis of 1,2-dihydroxynaphthalene dioxygenase from Pseudomonas sp. strain C18 complexed with 3,4-dihydroxybiphenyl'''
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==See Also==
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*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2EI0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI0 OCA].
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[[Category: Large Structures]]
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[[Category: Pseudomonas sp.]]
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[[Category: Pseudomonas sp. C18]]
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[[Category: Single protein]]
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[[Category: Bolin JT]]
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[[Category: Bolin, J T.]]
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[[Category: Colbert CL]]
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[[Category: Colbert, C L.]]
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[[Category: Kelker MS]]
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[[Category: Kelker, M S.]]
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[[Category: Neau DB]]
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[[Category: Neau, D B.]]
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[[Category: BP7]]
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[[Category: FE2]]
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[[Category: GOL]]
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[[Category: MG]]
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[[Category: extradiol dioxygenase]]
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[[Category: oxidoreductase]]
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[[Category: protein substrate complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:40:24 2008''
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Current revision

Anaerobic Crystal Structure Analysis of 1,2-dihydroxynaphthalene dioxygenase from Pseudomonas sp. strain C18 complexed with 3,4-dihydroxybiphenyl

PDB ID 2ei0

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