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2ejw

From Proteopedia

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[[Image:2ejw.jpg|left|200px]]
 
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{{Structure
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==Homoserine Dehydrogenase from Thermus thermophilus HB8==
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|PDB= 2ejw |SIZE=350|CAPTION= <scene name='initialview01'>2ejw</scene>, resolution 1.70&Aring;
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<StructureSection load='2ejw' size='340' side='right'caption='[[2ejw]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Residue+A+2003'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+B+2001'>AC2</scene>, <scene name='pdbsite=AC3:Mg+Binding+Site+For+Residue+A+2002'>AC3</scene>, <scene name='pdbsite=AC4:Mg+Binding+Site+For+Residue+B+2004'>AC4</scene>, <scene name='pdbsite=AC5:Mg+Binding+Site+For+Residue+F+2005'>AC5</scene>, <scene name='pdbsite=AC6:Mg+Binding+Site+For+Residue+E+2006'>AC6</scene>, <scene name='pdbsite=AC7:Mg+Binding+Site+For+Residue+E+2007'>AC7</scene>, <scene name='pdbsite=AC8:No3+Binding+Site+For+Residue+E+2601'>AC8</scene>, <scene name='pdbsite=AC9:No3+Binding+Site+For+Residue+A+2602'>AC9</scene>, <scene name='pdbsite=BC1:No3+Binding+Site+For+Residue+F+2603'>BC1</scene>, <scene name='pdbsite=BC2:Gol+Binding+Site+For+Residue+B+2501'>BC2</scene> and <scene name='pdbsite=BC3:Gol+Binding+Site+For+Residue+E+2502'>BC3</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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<table><tr><td colspan='2'>[[2ejw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EJW FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Homoserine_dehydrogenase Homoserine dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.3 1.1.1.3]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ejw OCA], [https://pdbe.org/2ejw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ejw RCSB], [https://www.ebi.ac.uk/pdbsum/2ejw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ejw ProSAT], [https://www.topsan.org/Proteins/RSGI/2ejw TOPSAN]</span></td></tr>
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</table>
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'''Homoserine Dehydrogenase from Thermus thermophilus HB8'''
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== Function ==
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[https://www.uniprot.org/uniprot/Q5SL04_THET8 Q5SL04_THET8]
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2EJW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJW OCA].
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Check<jmol>
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[[Category: Homoserine dehydrogenase]]
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<jmolCheckbox>
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[[Category: Single protein]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/2ejw_consurf.spt"</scriptWhenChecked>
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[[Category: Thermus thermophilus]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Goto, M.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Hirotsu, K.]]
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</jmolCheckbox>
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[[Category: Miyahara, I.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ejw ConSurf].
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[[Category: Omi, R.]]
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<div style="clear:both"></div>
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[[Category: GOL]]
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__TOC__
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[[Category: MG]]
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</StructureSection>
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[[Category: NO3]]
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[[Category: Large Structures]]
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[[Category: dehydrogenase]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: nad-dependent]]
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[[Category: Goto M]]
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[[Category: oxidoreductase]]
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[[Category: Hirotsu K]]
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[[Category: Miyahara I]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:41:16 2008''
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[[Category: Omi R]]

Current revision

Homoserine Dehydrogenase from Thermus thermophilus HB8

PDB ID 2ejw

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