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4jvy

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==Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA==
==Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA==
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<StructureSection load='4jvy' size='340' side='right' caption='[[4jvy]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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<StructureSection load='4jvy' size='340' side='right'caption='[[4jvy]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4jvy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JVY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4jvy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JVY FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jvh|4jvh]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jvy OCA], [https://pdbe.org/4jvy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jvy RCSB], [https://www.ebi.ac.uk/pdbsum/4jvy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jvy ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gld-1, T23G11.3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jvy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jvy RCSB], [http://www.ebi.ac.uk/pdbsum/4jvy PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GLD1_CAEEL GLD1_CAEEL]] Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation.
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[https://www.uniprot.org/uniprot/GLD1_CAEEL GLD1_CAEEL] Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4jvy" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
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[[Category: Essig, K]]
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[[Category: Large Structures]]
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[[Category: Hafner, M]]
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[[Category: Essig K]]
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[[Category: Patel, D J]]
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[[Category: Hafner M]]
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[[Category: Teplov, D]]
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[[Category: Patel DJ]]
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[[Category: Teplova, M]]
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[[Category: Teplov D]]
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[[Category: Tuschl, T]]
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[[Category: Teplova M]]
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[[Category: Kh domain]]
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[[Category: Tuschl T]]
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[[Category: Rna binding protein]]
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[[Category: Rna regulation]]
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[[Category: Star domain]]
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[[Category: Translational repression. rna binding protein]]
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Current revision

Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA

PDB ID 4jvy

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