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4nq5

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==Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 complexed with compound CS319==
==Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 complexed with compound CS319==
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<StructureSection load='4nq5' size='340' side='right' caption='[[4nq5]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
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<StructureSection load='4nq5' size='340' side='right'caption='[[4nq5]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nq5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NQ5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nq5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NQ5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3C7:(3R,5R,7AS)-5-(SULFANYLMETHYL)TETRAHYDRO[1,3]THIAZOLO[4,3-B][1,3]THIAZOLE-3-CARBOXYLIC+ACID'>3C7</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nq4|4nq4]], [[4nq6|4nq6]], [[4nq7|4nq7]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3C7:(3R,5R,7AS)-5-(SULFANYLMETHYL)TETRAHYDRO[1,3]THIAZOLO[4,3-B][1,3]THIAZOLE-3-CARBOXYLIC+ACID'>3C7</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nq5 OCA], [https://pdbe.org/4nq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nq5 RCSB], [https://www.ebi.ac.uk/pdbsum/4nq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nq5 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nq5 RCSB], [http://www.ebi.ac.uk/pdbsum/4nq5 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE]] Can hydrolyze carbapenem compounds.
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[https://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE] Can hydrolyze carbapenem compounds.
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Bacillus cereus]]
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[[Category: Gonzalez, J M]]
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[[Category: Large Structures]]
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[[Category: Gonzalez, M M]]
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[[Category: Gonzalez JM]]
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[[Category: Vila, A J]]
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[[Category: Gonzalez MM]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Vila AJ]]
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[[Category: Lactamase]]
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[[Category: Metallo-beta-lactamase superfamily]]
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Current revision

Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 complexed with compound CS319

PDB ID 4nq5

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