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2a08

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==Structure of the yeast YHH6 SH3 domain==
==Structure of the yeast YHH6 SH3 domain==
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<StructureSection load='2a08' size='340' side='right' caption='[[2a08]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
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<StructureSection load='2a08' size='340' side='right'caption='[[2a08]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2a08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A08 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2a08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A08 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oot|1oot]], [[1ruw|1ruw]], [[1ssh|1ssh]], [[1tg0|1tg0]], [[1va7|1va7]], [[1wdx|1wdx]], [[1yn8|1yn8]], [[1ynz|1ynz]], [[1yp5|1yp5]], [[1z9z|1z9z]], [[1zuk|1zuk]], [[1zuu|1zuu]], [[1zuy|1zuy]], [[1zx6|1zx6]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a08 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2a08 RCSB], [http://www.ebi.ac.uk/pdbsum/2a08 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a08 OCA], [https://pdbe.org/2a08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a08 RCSB], [https://www.ebi.ac.uk/pdbsum/2a08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a08 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/YSC84_YEAST YSC84_YEAST]] Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking, together with LSB5.<ref>PMID:12388763</ref>
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[https://www.uniprot.org/uniprot/YSC84_YEAST YSC84_YEAST] Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking, together with LSB5.<ref>PMID:12388763</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a0/2a08_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a0/2a08_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a08 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Kursula, I]]
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[[Category: Kursula I]]
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[[Category: Kursula, P]]
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[[Category: Kursula P]]
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[[Category: Lehmann, F]]
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[[Category: Lehmann F]]
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[[Category: Song, Y H]]
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[[Category: Song YH]]
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[[Category: Wilmanns, M]]
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[[Category: Wilmanns M]]
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[[Category: Zou, P]]
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[[Category: Zou P]]
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[[Category: Protein binding]]
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[[Category: Sh3 domain]]
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[[Category: Structural genomic]]
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[[Category: Yeast]]
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Current revision

Structure of the yeast YHH6 SH3 domain

PDB ID 2a08

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