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2f3b

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[[Image:2f3b.gif|left|200px]]
 
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{{Structure
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==Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase==
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|PDB= 2f3b |SIZE=350|CAPTION= <scene name='initialview01'>2f3b</scene>, resolution 1.800&Aring;
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<StructureSection load='2f3b' size='340' side='right'caption='[[2f3b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
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<table><tr><td colspan='2'>[[2f3b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F3B FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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|GENE= FBP1,FBP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 Sus scrofa])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f3b OCA], [https://pdbe.org/2f3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f3b RCSB], [https://www.ebi.ac.uk/pdbsum/2f3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f3b ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/F16P1_PIG F16P1_PIG]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f3/2f3b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f3b ConSurf].
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<div style="clear:both"></div>
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'''Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase'''
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==See Also==
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*[[Fructose-1%2C6-bisphosphatase 3D structures|Fructose-1%2C6-bisphosphatase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2F3B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F3B OCA].
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[[Category: Large Structures]]
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[[Category: Fructose-bisphosphatase]]
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[[Category: Single protein]]
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[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Choe, J Y.]]
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[[Category: Choe J-Y]]
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[[Category: Fromm, H J.]]
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[[Category: Fromm HJ]]
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[[Category: Honzatko, R B.]]
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[[Category: Honzatko RB]]
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[[Category: Iancu, C V.]]
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[[Category: Iancu CV]]
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[[Category: Mukund, S.]]
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[[Category: Mukund S]]
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[[Category: F6P]]
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[[Category: PO4]]
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[[Category: ZN]]
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[[Category: 6-bisphosphatase]]
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[[Category: allosteric regulation]]
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[[Category: allostery]]
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[[Category: enzyme catalysis]]
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[[Category: fbpase]]
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[[Category: fructose-1]]
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[[Category: loop diengagement]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:47:34 2008''
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Current revision

Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase

PDB ID 2f3b

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