3vr1

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==Crystal structure analysis of the translation factor RF3==
==Crystal structure analysis of the translation factor RF3==
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<StructureSection load='3vr1' size='340' side='right' caption='[[3vr1]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='3vr1' size='340' side='right'caption='[[3vr1]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vr1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._'miyazaki_f' Desulfovibrio vulgaris str. 'miyazaki f']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VR1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VR1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vr1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._'Miyazaki_F' Desulfovibrio vulgaris str. 'Miyazaki F']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VR1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G4P:GUANOSINE-5,3-TETRAPHOSPHATE'>G4P</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vqt|3vqt]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G4P:GUANOSINE-5,3-TETRAPHOSPHATE'>G4P</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DvMF_2372, prfC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=883 Desulfovibrio vulgaris str. 'Miyazaki F'])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vr1 OCA], [https://pdbe.org/3vr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vr1 RCSB], [https://www.ebi.ac.uk/pdbsum/3vr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vr1 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vr1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vr1 RCSB], [http://www.ebi.ac.uk/pdbsum/3vr1 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RF3_DESVM RF3_DESVM]] Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity).
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[https://www.uniprot.org/uniprot/RF3_DESVM RF3_DESVM] Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3vr1" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Desulfovibrio vulgaris str. 'miyazaki f']]
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[[Category: Desulfovibrio vulgaris str. 'Miyazaki F']]
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[[Category: Higuchi, Y]]
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[[Category: Large Structures]]
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[[Category: Kihira, K]]
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[[Category: Higuchi Y]]
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[[Category: Kitamura, M]]
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[[Category: Kihira K]]
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[[Category: Shibata, N]]
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[[Category: Kitamura M]]
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[[Category: Shomura, Y]]
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[[Category: Shibata N]]
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[[Category: Gtpase]]
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[[Category: Shomura Y]]
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[[Category: Release factor]]
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[[Category: Translation]]
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Current revision

Crystal structure analysis of the translation factor RF3

PDB ID 3vr1

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