2f7s
From Proteopedia
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| - | [[Image:2f7s.gif|left|200px]]  | ||
| - | + | ==The crystal structure of human Rab27b bound to GDP==  | |
| - | + | <StructureSection load='2f7s' size='340' side='right'caption='[[2f7s]], [[Resolution|resolution]] 2.70Å' scene=''>  | |
| - | + | == Structural highlights ==  | |
| - | |  | + | <table><tr><td colspan='2'>[[2f7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F7S FirstGlance]. <br>  | 
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr>  | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>  | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f7s OCA], [https://pdbe.org/2f7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f7s RCSB], [https://www.ebi.ac.uk/pdbsum/2f7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f7s ProSAT]</span></td></tr>  | |
| + | </table>  | ||
| + | == Function ==  | ||
| + | [https://www.uniprot.org/uniprot/RB27B_HUMAN RB27B_HUMAN] May be involved in targeting uroplakins to urothelial apical membranes (By similarity).  | ||
| + | == Evolutionary Conservation ==  | ||
| + | [[Image:Consurf_key_small.gif|200px|right]]  | ||
| + | Check<jmol>  | ||
| + |   <jmolCheckbox>  | ||
| + |     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/2f7s_consurf.spt"</scriptWhenChecked>  | ||
| + |     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>  | ||
| + |     <text>to colour the structure by Evolutionary Conservation</text>  | ||
| + |   </jmolCheckbox>  | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f7s ConSurf].  | ||
| + | <div style="clear:both"></div>  | ||
| - | + | ==See Also==  | |
| - | + | *[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]  | |
| - | + | __TOC__  | |
| - | ==  | + | </StructureSection>  | 
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[[Category: Homo sapiens]]  | [[Category: Homo sapiens]]  | ||
| - | [[Category:   | + | [[Category: Large Structures]]  | 
| - | [[Category: Arrowsmith  | + | [[Category: Arrowsmith CH]]  | 
| - | [[Category: Bochkarev  | + | [[Category: Bochkarev A]]  | 
| - | [[Category: Edwards  | + | [[Category: Edwards AM]]  | 
| - | [[Category: Ismail  | + | [[Category: Ismail S]]  | 
| - | [[Category: Park  | + | [[Category: Park HW]]  | 
| - | + | [[Category: Shen Y]]  | |
| - | [[Category: Shen  | + | [[Category: Sundstrom M]]  | 
| - | [[Category: Sundstrom  | + | [[Category: Tempel W]]  | 
| - | [[Category: Tempel  | + | [[Category: Wang J]]  | 
| - | [[Category: Wang  | + | |
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Current revision
The crystal structure of human Rab27b bound to GDP
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Edwards AM | Ismail S | Park HW | Shen Y | Sundstrom M | Tempel W | Wang J

