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2m28
From Proteopedia
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==NMR structure of Ca2+ bound CaBP4 C-domain== | ==NMR structure of Ca2+ bound CaBP4 C-domain== | ||
| - | <StructureSection load='2m28' size='340' side='right' caption='[[2m28 | + | <StructureSection load='2m28' size='340' side='right'caption='[[2m28]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2m28]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M28 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[2m28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M28 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m28 OCA], [https://pdbe.org/2m28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m28 RCSB], [https://www.ebi.ac.uk/pdbsum/2m28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m28 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CABP4_MOUSE CABP4_MOUSE] Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages.<ref>PMID:15452577</ref> <ref>PMID:16249514</ref> <ref>PMID:17050707</ref> <ref>PMID:17947313</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| + | [[Category: Ames JB]] | ||
Current revision
NMR structure of Ca2+ bound CaBP4 C-domain
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