This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ko6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:45, 7 February 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of yeast free methionine-R-sulfoxide reductase Ykg9 in complex with the substrate==
==Crystal structure of yeast free methionine-R-sulfoxide reductase Ykg9 in complex with the substrate==
-
<StructureSection load='3ko6' size='340' side='right' caption='[[3ko6]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
+
<StructureSection load='3ko6' size='340' side='right'caption='[[3ko6]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3ko6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KO6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KO6 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3ko6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KO6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KO6 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YKL069W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-methionine_(R)-S-oxide_reductase L-methionine (R)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.14 1.8.4.14] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ko6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ko6 OCA], [https://pdbe.org/3ko6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ko6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ko6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ko6 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ko6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ko6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ko6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ko6 PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/YKG9_YEAST YKG9_YEAST]] Catalyzes the reversible oxidation-reduction of the R-enantiomer of free methionine sulfoxide to methionine. Does not act on S-enantiomer of free methionine sulfoxide or R-enantiomer of dabsylated methionine sulfoxide. Involved in protection against oxidative stress.<ref>PMID:19049972</ref>
+
[https://www.uniprot.org/uniprot/FRMSR_YEAST FRMSR_YEAST] Catalyzes the reversible oxidation-reduction of the R-enantiomer of free methionine sulfoxide to methionine. Does not act on S-enantiomer of free methionine sulfoxide or R-enantiomer of dabsylated methionine sulfoxide. Involved in protection against oxidative stress.<ref>PMID:19049972</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Saccharomyces cerevisiae]]
+
[[Category: Large Structures]]
-
[[Category: Chen, Y]]
+
[[Category: Saccharomyces cerevisiae S288C]]
-
[[Category: Guo, P C]]
+
[[Category: Chen Y]]
-
[[Category: Ma, X X]]
+
[[Category: Guo P-C]]
-
[[Category: Zhou, C Z]]
+
[[Category: Ma X-X]]
-
[[Category: Catalytic mechanism]]
+
[[Category: Zhou C-Z]]
-
[[Category: Methionine-r-sulfoxide reductase]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Product dissociation]]
+
-
[[Category: Substrate binding]]
+

Current revision

Crystal structure of yeast free methionine-R-sulfoxide reductase Ykg9 in complex with the substrate

PDB ID 3ko6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools