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2o2l
From Proteopedia
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==Crystal structure of human heat-labile enterotoxin in complex with a blood group A antigen analog== | ==Crystal structure of human heat-labile enterotoxin in complex with a blood group A antigen analog== | ||
| - | <StructureSection load='2o2l' size='340' side='right' caption='[[2o2l]], [[Resolution|resolution]] 2.53Å' scene=''> | + | <StructureSection load='2o2l' size='340' side='right'caption='[[2o2l]], [[Resolution|resolution]] 2.53Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2o2l]] is a 10 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2o2l]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O2L FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o2l OCA], [https://pdbe.org/2o2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o2l RCSB], [https://www.ebi.ac.uk/pdbsum/2o2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o2l ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ELBH_ECOLX ELBH_ECOLX] The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2o2l" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Askarieh | + | [[Category: Large Structures]] |
| - | [[Category: Holmner | + | [[Category: Askarieh G]] |
| - | [[Category: Krengel | + | [[Category: Holmner A]] |
| - | [[Category: Okvist | + | [[Category: Krengel U]] |
| - | + | [[Category: Okvist M]] | |
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Current revision
Crystal structure of human heat-labile enterotoxin in complex with a blood group A antigen analog
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