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3zq1

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==Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein==
==Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein==
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<StructureSection load='3zq1' size='340' side='right' caption='[[3zq1]], [[Resolution|resolution]] 15.90&Aring;' scene=''>
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<SX load='3zq1' size='340' side='right' viewer='molstar' caption='[[3zq1]], [[Resolution|resolution]] 15.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zq1]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21 Escherichia coli bl21] and [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZQ1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zq1]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZQ1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 15.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zpz|3zpz]], [[3zq0|3zq0]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zq1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zq1 RCSB], [http://www.ebi.ac.uk/pdbsum/3zq1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zq1 OCA], [https://pdbe.org/3zq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zq1 RCSB], [https://www.ebi.ac.uk/pdbsum/3zq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zq1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/CH10_ECOLI CH10_ECOLI]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.[HAMAP-Rule:MF_00580]
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[https://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3zq1" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Chaperonin|Chaperonin]]
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*[[Chaperonin 3D structures|Chaperonin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Escherichia coli bl21]]
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[[Category: Escherichia coli BL21]]
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[[Category: Escherichia coli k-12]]
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[[Category: Escherichia coli K-12]]
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[[Category: Chen, D H]]
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[[Category: Large Structures]]
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[[Category: Chiu, W]]
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[[Category: Chen D-H]]
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[[Category: Lin, Z]]
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[[Category: Chiu W]]
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[[Category: Madan, D]]
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[[Category: Lin Z]]
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[[Category: Rye, H S]]
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[[Category: Madan D]]
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[[Category: Schroder, G F]]
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[[Category: Rye HS]]
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[[Category: Weaver, J]]
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[[Category: Schroder GF]]
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[[Category: Chaperone]]
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[[Category: Weaver J]]
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[[Category: Encapsulation]]
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[[Category: Rubisco]]
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Current revision

Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein

3zq1, resolution 15.90Å

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