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4kjz

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==Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474)==
==Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474)==
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<StructureSection load='4kjz' size='340' side='right' caption='[[4kjz]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='4kjz' size='340' side='right'caption='[[4kjz]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4kjz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KJZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KJZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4kjz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KJZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">infB, TTHA0699 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 Thermus thermophilus HB8])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kjz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kjz RCSB], [http://www.ebi.ac.uk/pdbsum/4kjz PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kjz OCA], [https://pdbe.org/4kjz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kjz RCSB], [https://www.ebi.ac.uk/pdbsum/4kjz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kjz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8]] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
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[https://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4kjz" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thermus thermophilus hb8]]
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[[Category: Large Structures]]
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[[Category: Eiler, D R]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Lin, J]]
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[[Category: Eiler DR]]
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[[Category: Steitz, T A]]
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[[Category: Lin J]]
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[[Category: Gtp]]
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[[Category: Steitz TA]]
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[[Category: Gtpase]]
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[[Category: Translation]]
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[[Category: Translation initiation factor/if2 superfamily]]
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Current revision

Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474)

PDB ID 4kjz

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