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2for

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[[Image:2for.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate==
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|PDB= 2for |SIZE=350|CAPTION= <scene name='initialview01'>2for</scene>, resolution 2.00&Aring;
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<StructureSection load='2for' size='340' side='right'caption='[[2for]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=IPR:ISOPENTYL PYROPHOSPHATE'>IPR</scene>
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<table><tr><td colspan='2'>[[2for]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FOR FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Geranyltranstransferase Geranyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.10 2.5.1.10]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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|GENE= AAP15892 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 Shigella flexneri])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPR:ISOPENTYL+PYROPHOSPHATE'>IPR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2for FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2for OCA], [https://pdbe.org/2for PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2for RCSB], [https://www.ebi.ac.uk/pdbsum/2for PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2for ProSAT], [https://www.topsan.org/Proteins/MCSG/2for TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0H2UXE9_SHIFL A0A0H2UXE9_SHIFL]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/2for_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2for ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate'''
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==See Also==
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*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2FOR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOR OCA].
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[[Category: Large Structures]]
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[[Category: Geranyltranstransferase]]
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[[Category: Shigella flexneri]]
[[Category: Shigella flexneri]]
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[[Category: Single protein]]
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[[Category: Anderson WF]]
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[[Category: Anderson, W F.]]
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[[Category: Brunzelle JS]]
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[[Category: Brunzelle, J S.]]
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[[Category: Collart FR]]
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[[Category: Collart, F R.]]
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[[Category: Joachimiak A]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Minasov G]]
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[[Category: Minasov, G.]]
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[[Category: Shuvalova L]]
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[[Category: Shuvalova, L.]]
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[[Category: IPR]]
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[[Category: PO4]]
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[[Category: bisphosphonate; isoprenyl synthase]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:55:00 2008''
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Current revision

Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate

PDB ID 2for

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