2mxb

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m (Protected "2mxb" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 2mxb is ON HOLD
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==Structure of the transmembrane domain of the mouse erythropoietin receptor==
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<StructureSection load='2mxb' size='340' side='right'caption='[[2mxb]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2mxb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MXB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxb OCA], [https://pdbe.org/2mxb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mxb RCSB], [https://www.ebi.ac.uk/pdbsum/2mxb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mxb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EPOR_MOUSE EPOR_MOUSE] Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.<ref>PMID:8382775</ref> <ref>PMID:8617735</ref>
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Authors: Li, Q., Wong, Y., Lee, M., Kang, C.
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==See Also==
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*[[Erythropoietin receptor|Erythropoietin receptor]]
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Description: Structure of the transmembrane domain of the erythropoietin receptor
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Kang, C]]
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__TOC__
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[[Category: Li, Q]]
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</StructureSection>
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[[Category: Wong, Y]]
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[[Category: Large Structures]]
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[[Category: Lee, M]]
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[[Category: Mus musculus]]
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[[Category: Kang C]]
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[[Category: Lee M]]
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[[Category: Li Q]]
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[[Category: Wong Y]]

Current revision

Structure of the transmembrane domain of the mouse erythropoietin receptor

PDB ID 2mxb

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