4uf1
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4uf1 is ON HOLD Authors: Burton, D.R., Kvansakul, M. Description: Deerpox virus DPV022 in complex with Bak BH3 Category: Unreleased Structures ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Deerpox virus DPV022 in complex with Bak BH3== | |
| - | + | <StructureSection load='4uf1' size='340' side='right'caption='[[4uf1]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4uf1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deerpox_virus_W-1170-84 Deerpox virus W-1170-84] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UF1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: Burton | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf1 OCA], [https://pdbe.org/4uf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uf1 RCSB], [https://www.ebi.ac.uk/pdbsum/4uf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uf1 ProSAT]</span></td></tr> |
| - | [[Category: Kvansakul | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPV22_DPV83 DPV22_DPV83] Plays a role in the inhibition of host apoptosis by sequestering and inactivating several proapoptotic BCL-2 proteins, including BAK1 and BAX. Prevents the conformational activation of both of them.<ref>PMID:21159883</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Deerpox virus W-1170-84]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Burton DR]] | ||
| + | [[Category: Kvansakul M]] | ||
Current revision
Deerpox virus DPV022 in complex with Bak BH3
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