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4uf6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==UCH-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G== | |
| + | <StructureSection load='4uf6' size='340' side='right'caption='[[4uf6]], [[Resolution|resolution]] 3.69Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4uf6]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UF6 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.69Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AYE:PROP-2-EN-1-AMINE'>AYE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uf6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf6 OCA], [https://pdbe.org/4uf6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uf6 RCSB], [https://www.ebi.ac.uk/pdbsum/4uf6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uf6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UCHL5_HUMAN UCHL5_HUMAN] Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.<ref>PMID:16906146</ref> <ref>PMID:18922472</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Thioesterase 3D structures|Thioesterase 3D structures]] | |
| - | + | *[[3D structures of ubiquitin|3D structures of ubiquitin]] | |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Ekkebus R]] |
| + | [[Category: El Oualid F]] | ||
| + | [[Category: Ovaa H]] | ||
| + | [[Category: Sahtoe DD]] | ||
| + | [[Category: Sixma TK]] | ||
| + | [[Category: Van Dijk WJ]] | ||
Current revision
UCH-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G
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Categories: Homo sapiens | Large Structures | Ekkebus R | El Oualid F | Ovaa H | Sahtoe DD | Sixma TK | Van Dijk WJ
