2g1w
From Proteopedia
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| - | [[Image:2g1w.gif|left|200px]] | ||
| - | + | ==NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1== | |
| - | + | <StructureSection load='2g1w' size='340' side='right'caption='[[2g1w]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2g1w]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G1W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | | | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g1w OCA], [https://pdbe.org/2g1w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g1w RCSB], [https://www.ebi.ac.uk/pdbsum/2g1w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g1w ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | + | <div style="background-color:#fffaf0;"> | |
| - | ''' | + | == Publication Abstract from PubMed == |
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The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation. | The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation. | ||
| - | + | NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation.,Nonin-Lecomte S, Felden B, Dardel F Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:16595798<ref>PMID:16595798</ref> | |
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| - | NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F | + | |
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| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| + | </div> | ||
| + | <div class="pdbe-citations 2g1w" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dardel F]] | ||
| + | [[Category: Nonin-Lecomte S]] | ||
Current revision
NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1
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