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3e8j

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==Coproporphyrinogen III oxidase from Leishmania naiffi==
==Coproporphyrinogen III oxidase from Leishmania naiffi==
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<StructureSection load='3e8j' size='340' side='right' caption='[[3e8j]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
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<StructureSection load='3e8j' size='340' side='right'caption='[[3e8j]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3e8j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_naiffi Leishmania naiffi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E8J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3e8j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_naiffi Leishmania naiffi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E8J FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vju|1vju]], [[2qt8|2qt8]], [[3dwr|3dwr]], [[3dws|3dws]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">similar to LbrM06_V2.1260 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5678 Leishmania naiffi])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e8j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e8j OCA], [https://pdbe.org/3e8j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e8j RCSB], [https://www.ebi.ac.uk/pdbsum/3e8j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e8j ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coproporphyrinogen_oxidase Coproporphyrinogen oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.3 1.3.3.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e8j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e8j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e8j RCSB], [http://www.ebi.ac.uk/pdbsum/3e8j PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D0VWU6_9TRYP D0VWU6_9TRYP]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e8/3e8j_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e8/3e8j_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e8j ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Coproporphyrinogen oxidase]]
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[[Category: Large Structures]]
[[Category: Leishmania naiffi]]
[[Category: Leishmania naiffi]]
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[[Category: Larson, E T]]
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[[Category: Larson ET]]
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[[Category: Structural genomic]]
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[[Category: Merritt EA]]
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[[Category: Merritt, E A]]
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[[Category: Heme biosynthesis]]
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[[Category: Heme metabolism]]
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[[Category: Msgpp]]
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[[Category: Oxidoreductase]]
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[[Category: Porphyrin biosynthesis]]
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Current revision

Coproporphyrinogen III oxidase from Leishmania naiffi

PDB ID 3e8j

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