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3r3e
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==The glutathione bound structure of YqjG, a glutathione transferase homolog from Escherichia coli K-12== | ==The glutathione bound structure of YqjG, a glutathione transferase homolog from Escherichia coli K-12== | ||
| - | <StructureSection load='3r3e' size='340' side='right' caption='[[3r3e]], [[Resolution|resolution]] 2.21Å' scene=''> | + | <StructureSection load='3r3e' size='340' side='right'caption='[[3r3e]], [[Resolution|resolution]] 2.21Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3r3e]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3r3e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R3E FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.205Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r3e OCA], [https://pdbe.org/3r3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r3e RCSB], [https://www.ebi.ac.uk/pdbsum/3r3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r3e ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/YQJG_ECOLI YQJG_ECOLI] Catalyzes glutathione (GSH)-dependent reduction of glutathionyl-hydroquinones (GS-HQs) to the corresponding hydroquinones. Can use a variety of GS-HQs as substrates, such as GS-p-hydroquinone (GS-HQ), GS-hydroxy-p-hydroquinone (GS-HHQ), GS-methyl-p-hydroquinone (GS-MHQ), GS-menadiol, and GS-trichloro-p-hydroquinone (GS-TriCH). Also displays GSH-dependent disulfide-bond reduction activity toward HED (2-hydroxyethyl disulfide), and is able to catalyze DMA (dimethylarsinate) reduction. Exhibits no GSH transferase activity with 1-chloro-2,4-dinitrobenzene (CDNB).<ref>PMID:20388120</ref> <ref>PMID:22686328</ref> <ref>PMID:22955277</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Escherichia coli]] | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Armstrong | + | [[Category: Armstrong RN]] |
| - | [[Category: Branch | + | [[Category: Branch MC]] |
| - | [[Category: Cook | + | [[Category: Cook PD]] |
| - | [[Category: Harp | + | [[Category: Harp JM]] |
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Current revision
The glutathione bound structure of YqjG, a glutathione transferase homolog from Escherichia coli K-12
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