2gdf

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[[Image:2gdf.gif|left|200px]]
 
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{{Structure
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==Crystal structure of Dioclea violacea seed lectin==
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|PDB= 2gdf |SIZE=350|CAPTION= <scene name='initialview01'>2gdf</scene>, resolution 2.40&Aring;
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<StructureSection load='2gdf' size='340' side='right'caption='[[2gdf]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
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<table><tr><td colspan='2'>[[2gdf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Macropsychanthus_violaceus Macropsychanthus violaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GDF FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gdf OCA], [https://pdbe.org/2gdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gdf RCSB], [https://www.ebi.ac.uk/pdbsum/2gdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gdf ProSAT]</span></td></tr>
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</table>
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'''Crystal structure of Dioclea violacea seed lectin'''
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== Function ==
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[https://www.uniprot.org/uniprot/LECA_DIOGR LECA_DIOGR] D-mannose/D-glucose-binding lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 50 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2GDF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dioclea_violacea Dioclea violacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GDF OCA].
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Check<jmol>
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[[Category: Dioclea violacea]]
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<jmolCheckbox>
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[[Category: Single protein]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/2gdf_consurf.spt"</scriptWhenChecked>
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[[Category: Cavada, B S.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Chornet, J J.C.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Sol, F Gallego del.]]
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</jmolCheckbox>
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[[Category: CA]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gdf ConSurf].
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[[Category: MN]]
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<div style="clear:both"></div>
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[[Category: plant lectin]]
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== References ==
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<references/>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:03:26 2008''
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Macropsychanthus violaceus]]
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[[Category: Cavada BS]]
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[[Category: Chornet JJC]]
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[[Category: Gallego del Sol F]]

Current revision

Crystal structure of Dioclea violacea seed lectin

PDB ID 2gdf

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