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3zmd

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==Crystal structure of AbsC, a MarR family transcriptional regulator from Streptomyces coelicolor==
==Crystal structure of AbsC, a MarR family transcriptional regulator from Streptomyces coelicolor==
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<StructureSection load='3zmd' size='340' side='right' caption='[[3zmd]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='3zmd' size='340' side='right'caption='[[3zmd]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zmd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZMD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zmd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZMD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zmd RCSB], [http://www.ebi.ac.uk/pdbsum/3zmd PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmd OCA], [https://pdbe.org/3zmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zmd RCSB], [https://www.ebi.ac.uk/pdbsum/3zmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zmd ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q9L2B5_STRCO Q9L2B5_STRCO]
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Crystals of recombinant AbsC (subunit MW = 18 313 Da; 158 amino acids), a novel regulator of antibiotic production from Streptomyces coelicolor, were grown by vapour diffusion. The protein crystallizes in space group P2(1)2(1)2(1), with unit-cell parameters a = 43.53, b = 121.30, c = 143.75 A. Native data to a resolution of 2.25 A were recorded at station PX 14.1 (Daresbury) from a single crystal. Preliminary analysis of these data suggests that the asymmetric unit contains four copies of the AbsC monomer, giving an estimated solvent content of 47.0%. AbsC belongs to the MarR family of proteins that mediate ligand-responsive transcriptional control.
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Crystallization and preliminary X-ray analysis of AbsC, a novel regulator of antibiotic production in Streptomyces coelicolor.,Stevenson CE, Kock H, Mootien S, Davies SC, Bibb MJ, Lawson DM Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt 3):233-5. Epub, 2007 Feb 23. PMID:17329821<ref>PMID:17329821</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
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[[Category: Bibb, M J]]
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[[Category: Bibb MJ]]
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[[Category: Davies, S C]]
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[[Category: Davies SC]]
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[[Category: Kock, H]]
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[[Category: Kock H]]
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[[Category: Lawson, D M]]
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[[Category: Lawson DM]]
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[[Category: Mootien, S]]
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[[Category: Mootien S]]
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[[Category: Stevenson, C E.M]]
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[[Category: Stevenson CEM]]
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[[Category: Marr-family]]
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[[Category: Transcription]]
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[[Category: Winged helix motif]]
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Current revision

Crystal structure of AbsC, a MarR family transcriptional regulator from Streptomyces coelicolor

PDB ID 3zmd

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