3tos

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==Crystal Structure of CalS11, Calicheamicin Methyltransferase==
==Crystal Structure of CalS11, Calicheamicin Methyltransferase==
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<StructureSection load='3tos' size='340' side='right' caption='[[3tos]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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<StructureSection load='3tos' size='340' side='right'caption='[[3tos]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3tos]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Micromonospora_echinospora Micromonospora echinospora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TOS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TOS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3tos]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Micromonospora_echinospora Micromonospora echinospora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TOS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">calS11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1877 Micromonospora echinospora])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tos OCA], [https://pdbe.org/3tos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tos RCSB], [https://www.ebi.ac.uk/pdbsum/3tos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tos ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tos OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tos RCSB], [http://www.ebi.ac.uk/pdbsum/3tos PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8KNF1_MICEC Q8KNF1_MICEC]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Micromonospora echinospora]]
[[Category: Micromonospora echinospora]]
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[[Category: Aceti, D J]]
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[[Category: Aceti DJ]]
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[[Category: Beebe, E T]]
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[[Category: Beebe ET]]
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[[Category: Bingman, C A]]
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[[Category: Bingman CA]]
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[[Category: Structural genomic]]
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[[Category: Chang A]]
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[[Category: Chang, A]]
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[[Category: Makino S-I]]
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[[Category: Makino, S I]]
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[[Category: Phillips Jr GN]]
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[[Category: NatPro, Enzyme Discovery for Natural Product Biosynthesis]]
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[[Category: Thorson JS]]
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[[Category: Phillips, G N]]
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[[Category: Wrobel RL]]
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[[Category: Thorson, J S]]
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[[Category: Wrobel, R L]]
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[[Category: Calicheamicin]]
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[[Category: Cals11]]
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[[Category: Cesg]]
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[[Category: Enzyme discovery for natural product biosynthesis]]
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[[Category: Methyltransferase]]
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[[Category: Natpro]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of CalS11, Calicheamicin Methyltransferase

PDB ID 3tos

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