3roh
From Proteopedia
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==Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.== | ==Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.== | ||
| - | <StructureSection load='3roh' size='340' side='right' caption='[[3roh]], [[Resolution|resolution]] 3.20Å' scene=''> | + | <StructureSection load='3roh' size='340' side='right'caption='[[3roh]], [[Resolution|resolution]] 3.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3roh]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3roh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_NCTC_8325 Staphylococcus aureus subsp. aureus NCTC 8325]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ROH FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3roh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3roh OCA], [https://pdbe.org/3roh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3roh RCSB], [https://www.ebi.ac.uk/pdbsum/3roh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3roh ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LUKEV_STAA8 LUKEV_STAA8] Part of a bi-component leucotoxin that acts by forming pores in the membrane of the target cells. The activity of LukEv-LukDv to rabbit leukocytes is similar to that of the Panton-Valentine leucocidin (PVL). LukEv-LukDv is hemolytic to rabbit red blood cells although the activity is only 8% of gamma-hemolysin.<ref>PMID:12636257</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Staphylococcus aureus subsp. aureus | + | [[Category: Large Structures]] |
| - | [[Category: Anderson | + | [[Category: Staphylococcus aureus subsp. aureus NCTC 8325]] |
| - | [[Category: Bagnoli | + | [[Category: Anderson WF]] |
| - | [[Category: Bottomley | + | [[Category: Bagnoli F]] |
| - | + | [[Category: Bottomley M]] | |
| - | [[Category: Dubrovska | + | [[Category: Dubrovska I]] |
| - | [[Category: Falugi | + | [[Category: Falugi F]] |
| - | [[Category: Grandi | + | [[Category: Grandi G]] |
| - | [[Category: Halavaty | + | [[Category: Halavaty A]] |
| - | [[Category: Minasov | + | [[Category: Minasov G]] |
| - | [[Category: Shuvalova | + | [[Category: Shuvalova L]] |
| - | [[Category: Winsor | + | [[Category: Winsor J]] |
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Current revision
Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.
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