3t7l
From Proteopedia
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==Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution== | ==Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution== | ||
| - | <StructureSection load='3t7l' size='340' side='right' caption='[[3t7l]], [[Resolution|resolution]] 1.09Å' scene=''> | + | <StructureSection load='3t7l' size='340' side='right'caption='[[3t7l]], [[Resolution|resolution]] 1.09Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3t7l]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3t7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7L FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.09Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7l OCA], [https://pdbe.org/3t7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7l RCSB], [https://www.ebi.ac.uk/pdbsum/3t7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7l ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ZFY16_HUMAN ZFY16_HUMAN] May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.<ref>PMID:11546807</ref> <ref>PMID:14613930</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Berridge | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Berridge G]] |
| - | [[Category: Bullock | + | [[Category: Bountra C]] |
| - | [[Category: Canning | + | [[Category: Bullock A]] |
| - | [[Category: Chaikuad | + | [[Category: Canning P]] |
| - | + | [[Category: Chaikuad A]] | |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Guo | + | [[Category: Guo K]] |
| - | [[Category: Krojer | + | [[Category: Krojer T]] |
| - | [[Category: Muniz | + | [[Category: Muniz JRC]] |
| - | [[Category: Phillips | + | [[Category: Phillips C]] |
| - | + | [[Category: Sanvitale C]] | |
| - | [[Category: Sanvitale | + | [[Category: Shrestha A]] |
| - | [[Category: Shrestha | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Williams E]] |
| - | [[Category: Williams | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
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Current revision
Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Berridge G | Bountra C | Bullock A | Canning P | Chaikuad A | Edwards AM | Guo K | Krojer T | Muniz JRC | Phillips C | Sanvitale C | Shrestha A | Weigelt J | Williams E | Von Delft F
