3zz6

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==Crystal structure of 3C protease of coxsackievirus B3 complexed with Michael receptor inhibitor 75==
==Crystal structure of 3C protease of coxsackievirus B3 complexed with Michael receptor inhibitor 75==
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<StructureSection load='3zz6' size='340' side='right' caption='[[3zz6]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='3zz6' size='340' side='right'caption='[[3zz6]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zz6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_coxsackievirus_b3 Human coxsackievirus b3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZZ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZZ6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zz6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxsackievirus_B3 Coxsackievirus B3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZZ6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G75:ETHYL+(4R)-4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE'>G75</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zzb|3zzb]], [[3zzc|3zzc]], [[3zzd|3zzd]], [[3zz8|3zz8]], [[3zz7|3zz7]], [[3zz9|3zz9]], [[3zz3|3zz3]], [[3zyd|3zyd]], [[3zz5|3zz5]], [[3zz4|3zz4]], [[3zye|3zye]], [[3zza|3zza]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G75:ETHYL+(4R)-4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE'>G75</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Picornain_3C Picornain 3C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.28 3.4.22.28] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zz6 OCA], [https://pdbe.org/3zz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zz6 RCSB], [https://www.ebi.ac.uk/pdbsum/3zz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zz6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zz6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zz6 RCSB], [http://www.ebi.ac.uk/pdbsum/3zz6 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5UEA2_9ENTO Q5UEA2_9ENTO]
==See Also==
==See Also==
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*[[3C protease|3C protease]]
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*[[Virus protease 3D structures|Virus protease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human coxsackievirus b3]]
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[[Category: Coxsackievirus B3]]
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[[Category: Picornain 3C]]
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[[Category: Large Structures]]
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[[Category: Anand, K]]
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[[Category: Anand K]]
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[[Category: Hilgenfeld, R]]
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[[Category: Hilgenfeld R]]
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[[Category: Mesters, J R]]
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[[Category: Mesters JR]]
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[[Category: Tan, J]]
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[[Category: Tan J]]
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[[Category: Hydrolase]]
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[[Category: Michael receptor inhibitor]]
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[[Category: Picornaviridae]]
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Current revision

Crystal structure of 3C protease of coxsackievirus B3 complexed with Michael receptor inhibitor 75

PDB ID 3zz6

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