2gqu

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[[Image:2gqu.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of UDP-N-Acetylenolpyruvylglucosamine Reductase (MurB) from Thermus caldophilus==
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|PDB= 2gqu |SIZE=350|CAPTION= <scene name='initialview01'>2gqu</scene>, resolution 1.60&Aring;
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<StructureSection load='2gqu' size='340' side='right'caption='[[2gqu]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene> and <scene name='pdbligand=EPU:URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID'>EPU</scene>
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<table><tr><td colspan='2'>[[2gqu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_caldophilus Thermus caldophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GQU FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/UDP-N-acetylmuramate_dehydrogenase UDP-N-acetylmuramate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.158 1.1.1.158]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPU:URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL)+BUTYRIC+ACID'>EPU</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gqu OCA], [https://pdbe.org/2gqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gqu RCSB], [https://www.ebi.ac.uk/pdbsum/2gqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gqu ProSAT]</span></td></tr>
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</table>
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'''Crystal Structure of UDP-N-Acetylenolpyruvylglucosamine Reductase (MurB) from Thermus caldophilus'''
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== Function ==
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[https://www.uniprot.org/uniprot/MURB_THET8 MURB_THET8] Cell wall formation.[HAMAP-Rule:MF_00037]
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2GQU is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_caldophilus Thermus caldophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQU OCA].
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Check<jmol>
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<jmolCheckbox>
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==Reference==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/2gqu_consurf.spt"</scriptWhenChecked>
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Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus., Kim MK, Cho MK, Song HE, Kim D, Park BH, Lee JH, Kang GB, Kim SH, Im YJ, Lee DS, Eom SH, Proteins. 2007 Feb 15;66(3):751-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17120230 17120230]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Protein complex]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gqu ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus caldophilus]]
[[Category: Thermus caldophilus]]
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[[Category: UDP-N-acetylmuramate dehydrogenase]]
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[[Category: Eom SH]]
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[[Category: Eom, S H.]]
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[[Category: Kim M-K]]
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[[Category: Kim, M K.]]
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[[Category: EPU]]
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[[Category: FAD]]
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[[Category: enolpyruvyl-udp-n-acetylglucosamine]]
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[[Category: enzyme]]
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[[Category: flavin adenine dinucleotide]]
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[[Category: peptidoglycan biosynthesis]]
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[[Category: substrate complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:07:55 2008''
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Current revision

Crystal Structure of UDP-N-Acetylenolpyruvylglucosamine Reductase (MurB) from Thermus caldophilus

PDB ID 2gqu

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