This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4ads
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of plasmodial PLP synthase complex== | ==Crystal structure of plasmodial PLP synthase complex== | ||
| - | <StructureSection load='4ads' size='340' side='right' caption='[[4ads]], [[Resolution|resolution]] 3.61Å' scene=''> | + | <StructureSection load='4ads' size='340' side='right'caption='[[4ads]], [[Resolution|resolution]] 3.61Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ads]] is a 12 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4ads]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_berghei Plasmodium berghei] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ADS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ADS FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.61Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ads FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ads OCA], [https://pdbe.org/4ads PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ads RCSB], [https://www.ebi.ac.uk/pdbsum/4ads PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ads ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PDX2_PLAF7 PDX2_PLAF7] Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of Pdx1.<ref>PMID:15590634</ref> <ref>PMID:16339145</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 15: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4ads" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Plasmodium berghei]] | [[Category: Plasmodium berghei]] | ||
| - | [[Category: Plasmodium falciparum]] | + | [[Category: Plasmodium falciparum 3D7]] |
| - | [[Category: Guedez | + | [[Category: Guedez G]] |
| - | [[Category: Sinning | + | [[Category: Sinning I]] |
| - | [[Category: Tews | + | [[Category: Tews I]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of plasmodial PLP synthase complex
| |||||||||||
