3t1i

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==Crystal Structure of Human Mre11: Understanding Tumorigenic Mutations==
==Crystal Structure of Human Mre11: Understanding Tumorigenic Mutations==
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<StructureSection load='3t1i' size='340' side='right' caption='[[3t1i]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='3t1i' size='340' side='right'caption='[[3t1i]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3t1i]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T1I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T1I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3t1i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T1I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNGS1, MRE11, MRE11A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t1i OCA], [https://pdbe.org/3t1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t1i RCSB], [https://www.ebi.ac.uk/pdbsum/3t1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t1i ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t1i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t1i RCSB], [http://www.ebi.ac.uk/pdbsum/3t1i PDBsum]</span></td></tr>
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</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3t1i" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Chae, J]]
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[[Category: Large Structures]]
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[[Category: Cho, Y]]
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[[Category: Chae J]]
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[[Category: Kim, Y]]
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[[Category: Cho Y]]
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[[Category: Park, Y B]]
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[[Category: Kim Y]]
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[[Category: Dna repair]]
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[[Category: Park YB]]
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[[Category: Endonuclease]]
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[[Category: Exonuclease]]
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[[Category: Hydrolase]]
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[[Category: Metallophosphatase]]
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[[Category: Mrn complex]]
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[[Category: Nbs1]]
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[[Category: Rad50]]
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Current revision

Crystal Structure of Human Mre11: Understanding Tumorigenic Mutations

PDB ID 3t1i

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