This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4gir
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, ethylene glycol and sulfate bound (ordered loops, space group P41212)== | ==Crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, ethylene glycol and sulfate bound (ordered loops, space group P41212)== | ||
| - | <StructureSection load='4gir' size='340' side='right' caption='[[4gir]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='4gir' size='340' side='right'caption='[[4gir]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4gir]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4gir]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_harveyi_1DA3 Vibrio harveyi 1DA3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GIR FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gir OCA], [https://pdbe.org/4gir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gir RCSB], [https://www.ebi.ac.uk/pdbsum/4gir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gir ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/IMAND_VIBH1 IMAND_VIBH1] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref> |
==See Also== | ==See Also== | ||
| - | *[[Enolase|Enolase]] | + | *[[Enolase 3D structures|Enolase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Vibrio harveyi 1DA3]] |
| - | [[Category: | + | [[Category: Al Obaidi NF]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Bhosle R]] |
| - | [[Category: | + | [[Category: Chowdhury S]] |
| - | [[Category: | + | [[Category: Evans B]] |
| - | [[Category: | + | [[Category: Gerlt JA]] |
| - | [[Category: Hammonds | + | [[Category: Hammonds J]] |
| - | [[Category: Hillerich | + | [[Category: Hillerich B]] |
| - | [[Category: Imker | + | [[Category: Imker HJ]] |
| - | [[Category: Love | + | [[Category: Love J]] |
| - | [[Category: Morisco | + | [[Category: Morisco LL]] |
| - | [[Category: | + | [[Category: Scott Glenn A]] |
| - | [[Category: Seidel | + | [[Category: Seidel RD]] |
| - | [[Category: Sojitra | + | [[Category: Sojitra S]] |
| - | [[Category: Toro | + | [[Category: Toro R]] |
| - | [[Category: Vetting | + | [[Category: Vetting MW]] |
| - | [[Category: Washington | + | [[Category: Washington E]] |
| - | [[Category: Wasserman | + | [[Category: Wasserman SR]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, ethylene glycol and sulfate bound (ordered loops, space group P41212)
| |||||||||||
Categories: Large Structures | Vibrio harveyi 1DA3 | Al Obaidi NF | Almo SC | Bhosle R | Chowdhury S | Evans B | Gerlt JA | Hammonds J | Hillerich B | Imker HJ | Love J | Morisco LL | Scott Glenn A | Seidel RD | Sojitra S | Toro R | Vetting MW | Washington E | Wasserman SR
