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4cb6

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==Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 11)==
==Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 11)==
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<StructureSection load='4cb6' size='340' side='right' caption='[[4cb6]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='4cb6' size='340' side='right'caption='[[4cb6]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/duck/shantou/4610/2003(h5n1)) Influenza a virus (a/duck/shantou/4610/2003(h5n1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CB6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4cb6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/duck/Shantou/4610/2003(H5N1)) Influenza A virus (A/duck/Shantou/4610/2003(H5N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CB6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=29R:2,9-N,N-DI(4-CARBOXYBUTYL)-7-N-METHYLGUANINE'>29R</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cb4|4cb4]], [[4cb5|4cb5]], [[4cb7|4cb7]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=29R:2,9-N,N-DI(4-CARBOXYBUTYL)-7-N-METHYLGUANINE'>29R</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cb6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cb6 RCSB], [http://www.ebi.ac.uk/pdbsum/4cb6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cb6 OCA], [https://pdbe.org/4cb6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cb6 RCSB], [https://www.ebi.ac.uk/pdbsum/4cb6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cb6 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q2LG68_9INFA Q2LG68_9INFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4cb6" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cusack, S]]
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[[Category: Large Structures]]
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[[Category: Decout, J L]]
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[[Category: Cusack S]]
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[[Category: Fortune, A]]
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[[Category: Decout JL]]
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[[Category: Gulligay, D]]
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[[Category: Fortune A]]
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[[Category: Lewis, J]]
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[[Category: Gulligay D]]
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[[Category: Lunardi, T]]
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[[Category: Lewis J]]
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[[Category: Pautus, S]]
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[[Category: Lunardi T]]
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[[Category: Sehr, P]]
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[[Category: Pautus S]]
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[[Category: Szolar, O]]
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[[Category: Sehr P]]
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[[Category: Wolkerstorfer, A]]
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[[Category: Szolar O]]
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[[Category: Cap-binding inhibitor]]
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[[Category: Wolkerstorfer A]]
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[[Category: Influenza polymerase]]
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[[Category: M7gtp]]
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[[Category: Transferase]]
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Current revision

Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 11)

PDB ID 4cb6

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